The Role of Connective Tissue Dysplasia in Post-Treatment Recurrences of Funnel Chest in Children

The article highlights the importance of biochemical investigations in children with thoracic cage whirl-like dysplastic deformities. Quantitative analyses of proline, hydroxyproline and glucosaminoglycans were carried out. The study was based on the examination results of 64 young children. The patients' medical history revealed that a whirlpool deformity was noted from an early age in 30 (58%) children, while in 12 (23%) patients, the disease manifested in the first year of life, In 10 (19%) children, the deformity appeared by the age of 3. The patients were divided into groups according to age for analysis. It was found that, depending on the degree of connective tissue dysplasia observed in the patients, the biochemical markers shifted in a positive direction following treatment.

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