EPIDEMIOLOGICAL CHARACTERISTICS OF CERVICAL INTRAEPITHELIAL NEOPLASIA ASSOCIATED WITH HUMAN PAPILLOMAVIRUS

Cervical intraepithelial neoplasia (CIN) is a common precancerous condition among women and represents a key precursor stage of cervical cancer. Modern epidemiological studies demonstrate that human papillomavirus (HPV), particularly high-risk types 16 and 18, plays a leading role in the development of CIN. According to available data, HPV is detected in 90–99% of CIN II–III cases (Schiffman et al., 1993). The widespread prevalence of HPV infection and its significant socio-economic burden determine the high relevance of this problem.

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