Мақола

Evaluating the impact of a structured digital health intervention on medication adherence in hypertensive patients

Jumayeva ZarnigorDepartment of Nephrology and Hemodialysis, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, UzbekistanPulatova ParizodaDepartment of Internal disease in Family medicine, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, UzbekistanXamidova ShaxloAssistant (Med.), Obstetrics and gynecology, Samarkand State Medical University, Samarkand, UzbekistanNamuna MadolimovaPhD, Department of Obstetrics and gynecology, reproductology, Tashkent state medical university, Tashkent, UzbekistanҲамдамов, Қодир Фозил ўғлиAssistant Pathological Physiology and Pathological Anatomy, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, UzbekistanJasurbek QoraboyevAssistant, Department of Traumatology and Orthopedics, Fergana Medical Institute of Public Health, Ferghana, UzbekistanKuziyeva GulruhAssistant and Independent Researcher, 1st Department of Obstetrics and Gynecology, Andijan State Medical Institute, Andijan, Uzbekistan;Kadirova LayloAssistant Pathological Physiology and Pathological Anatomy, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, UzbekistanAzizov DavronbekDepartment of Social and Humanitarian Sciences, Pedagogy and Psychology, Andijan State Institute of Foreign Languages, Andijan, Uzbekistan

Zenodo (CERN European Organization for Nuclear Research)repository2026en

ABI

Аннотация

Hypertension affects over 70% of diagnosed patients in Uzbekistan with poor control, largely due to medication non-adherence amid urbanization and limited resources. This trial evaluated a structured digital health intervention (DHI) a multilingual Android app with reminders, education, and gamification on adherence in primary care settings. In this prospective RCT across three Tashkent clinics (March 2024–December 2025), 320 adults (40–75 years) with essential hypertension (BP ≥140/90 mmHg on monotherapy) were randomized 1:1 to DHI plus standard care or standard care alone. Primary outcome: 12-month adherence (MMAS-8 score). Secondaries: BP control, quality of life (EQ-5D-5L), utilization. Analysis: intention-to-treat mixed models (P<0.05). Baseline balanced (mean age 58 years, MMAS-8 ~5). DHI boosted adherence (7.2 vs. 5.4; mean diff 1.8, 95% CI 1.5–2.1, P<0.001; high adherence 89% vs. 58%). BP fell more (SBP -14.2 mmHg, 78.7% controlled vs. 41.3%, OR 5.6; both P<0.001). Utilization dropped (visits RR 0.62), EQ-5D +0.10 (P<0.001). Engagement high (85% reminders).This culturally tailored DHI markedly improved adherence, BP, and outcomes in Uzbekistan, supporting scalable digital integration for hypertension management.

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Мавзулар

Mobile Health and mHealth Applications Medication Adherence and Compliance Blood Pressure and Hypertension Studies

Идентификаторлар

DOI: 10.5281/zenodo.19643616

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