Studies on the constituents of Scutellaria species. XI. On the flavonoid constituents of the aerial parts of Scutellaria indica L.

From the aerial parts of Scutellaria indica L., five new chalcones (I-V) were isolated, together with (2S)-5, 6, 7, 2', 3', 4', 5'-heptamethoxyflavanone, scutellarein 7-O-β-D-glucopyranoside, chrysin, apigenin, luteolin, scutellarein, isoscutellarein, chrysin 7-O-glucuronide, apigenin 7-O-glucuronide, scutellarin and isoscutellarein 8-O-glucuronide. The structures of I-V were shown to be 2'-hydroxy-2, 3, 4, 5, 4', 5', 6'-heptamethoxychalcone, 2, 3, 4, 5, 2', 4', 5', 6'-octamethoxychalcone, 2'-hydroxy-2, 3, 4, 5, 6'-pentamethoxy-4', 5'-methylenedioxychalcone, 2, 3, 4, 5, 2', 6'-hexamethoxy-4, 5-methylenedioxychalcone, 2, 2-dihydroxy-3, 4, 5, 6'-tetramethoxy-4', 5'-methylenedioxychalcone, respectively, on the basis of the chemical and spectral data. Compound I has already been synthesized.

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