Ameliorative Effect of<i>Silene aprica</i>on Liver Injuries Induced by Carbon Tetrachloride and Acetaminophen
Yu-Jen KoGraduate Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.CWen-Tsuan HsiehGraduate Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.CYueh-Wern WuDepartment of Pharmacology, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.CWen-Chuan LinDepartment of Pharmacology, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.C
2002en
ABI
Аннотация
The effect of oral administration of a 50% ethanol extract of Silene aprica (SA) on acute liver injury was examined in rats intoxicated with carbon tetrachloride (CCl4) and acetaminophen. The results indicated that SA protected the liver from CCl4- and acetaminophen-induced injury as judged by morphological and biochemical observations. An increase in both lipid peroxidation (LPO) and triglyceride concentrations occurred in the liver with CCl4 injection, SA administration significantly reduced these changes.
Ҳали таржима қилинмаган
Идентификаторлар
Иқтибослар ва манбалар
2 та иқтибос0 та фойдаланилган манба