Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents
Luling WuDepartment of ChemistryChusen HuangDepartment of ChemistryBen P. EmeryBathAdam C. SedgwickAustinSteven D. BullBathXiao‐Peng HeEast China University of Science and TechnologyHe TianEast China University of Science and TechnologyJuyoung YoonDepartment of Chemistry and Nano ScienceJonathan L. SesslerAustinTony D. JamesDepartment of Chemistry
2020en
ABI
Аннотация
In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.
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