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Иш: Synthesis of tricyclic pyrazolopyrimidine arylidene ester derivatives and their cytotoxic and molecular docking evaluations

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
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Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library
Buer Song, Lifei Nie, Khurshed Bozorov +3
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Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐a]thiazolo[5,4‐d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
Yan Zeng, Lifei Nie, Liu Liu +6
МақолаCholinesterase and Neurodegenerative DiseasesJournal of Heterocyclic Chemistry202217 иқтибос
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Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities
Buer Song, Lifei Nie, Khurshed Bozorov +3
МақолаSynthesis and Reactivity of Sulfur-Containing CompoundsResearch on Chemical Intermediates202216 иқтибос
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Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3- d ]pyrimidin-4(3 H )-ones and evaluation of their influence on melanin synthesis in murine B16 cells
Li Fei Nie, Guozheng Huang, Khurshed Bozorov +4
МақолаSynthesis of Organic CompoundsHeterocyclic Communications201815 иқтибос
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Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties
Khurshed Bozorov, Jiang-Yu Zhao, Burkhon Elmuradov +2
Шарҳ мақолаQuinazolinone synthesis and applicationsEuropean Journal of Medicinal Chemistry201514 иқтибос
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Synthesis and biological evaluation of novel sulfonamide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones on melanin synthesis in murine B16 cells
Li Fei Nie, Khurshed Bozorov, Chao Niu +2
Мақолаmelanin and skin pigmentationResearch on Chemical Intermediates201712 иқтибос
ABI
<scp>2‐substituted</scp> tricyclic oxazolo[5,4‐d]pyrimidine library: Design, synthesis, and cytotoxicity activity
Yan Zeng, Lifei Nie, Khurshed Bozorov +4
МақолаQuinazolinone synthesis and applicationsJournal of Heterocyclic Chemistry202111 иқтибос
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Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action
Zukela Ruzi, Khurshed Bozorov, Lifei Nie +2
МақолаSynthesis and biological activityBiomedicine & Pharmacotherapy20228 иқтибос
ABI
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy +1
Шарҳ мақола20015 иқтибос
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ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
Guo‐Li Xiong, Zhenhua Wu, Jiacai Yi +10
Мақола20214 иқтибос
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Inhibition of Leukocyte Functions by the Alkaloid Isaindigotone fromIsatis indigoticaand Some New Synthetic Derivatives
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Мақола20013 иқтибос
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Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review
Monika Chauhan, Raj Kumar
Шарҳ мақола20133 иқтибос
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Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors
Jason G. Kettle, Rana Anjum, Evan Barry +24
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Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate c-myc Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex
Chan Shan, Jinwu Yan, Yuqing Wang +9
Мақола20172 иқтибос
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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy
Brandt C. Huddle, Edward Grimley, Cameron D. Buchman +13
Мақола20182 иқтибос
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Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents
Kangjia Du, Wantong Ma, Cheng‐Jie Yang +10
Мақола20222 иқтибос
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A Novel Isaindigotone Derivative Displays Better Anti-Proliferation Activities and Induces Apoptosis in Gastric Cancer Cells
Kangjia Du, Cheng‐Jie Yang, Zhongkun Zhou +9
Мақола20222 иқтибос
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Rings in Drugs
Richard D. Taylor, Malcolm MacCoss, Alastair D. G. Lawson
Шарҳ мақола20142 иқтибос
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SwissParam: A fast force field generation tool for small organic molecules
Vincent Zoete, Michel A. Cuendet, Aurélien Grosdidier +1
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Ушбу иш иқтибос қилган ишлар

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Design, combinatorial synthesis and cytotoxic activity of 2-substituted furo[2,3-d]pyrimidinone and pyrrolo[2,3-d]pyrimidinone library

Design, synthesis, in vitro evaluation of a new pyrrolo[1,2‐<i>a</i>]thiazolo[5,4‐<i>d</i>]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease

Parallel synthesis of condensed pyrimidine-thiones and their antitumor activities

Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3- <i>d</i> ]pyrimidin-4(3 <i>H</i> )-ones and evaluation of their influence on melanin synthesis in murine B16 cells

Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties

Synthesis and biological evaluation of novel sulfonamide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones on melanin synthesis in murine B16 cells

<scp>2‐substituted</scp> tricyclic oxazolo[5,4‐<i>d</i>]pyrimidine library: Design, synthesis, and cytotoxicity activity

Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties

Inhibition of Leukocyte Functions by the Alkaloid Isaindigotone from<i>Isatis indigotica</i>and Some New Synthetic Derivatives

Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review

Discovery of <i>N</i>-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1<i>H</i>-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

Design, Synthesis, and Evaluation of Isaindigotone Derivatives To Downregulate <i>c-myc</i> Transcription via Disrupting the Interaction of NM23-H2 with G-Quadruplex

Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents

A Novel Isaindigotone Derivative Displays Better Anti-Proliferation Activities and Induces Apoptosis in Gastric Cancer Cells

Rings in Drugs

SwissParam: A fast force field generation tool for small organic molecules

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