Мақола

Solubility of Vitamin E Acetate in Supercritical Carbon Dioxide with Ethanol as Cosolvent

Jiangrui ChengSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, ChinaSai HanSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, ChinaJunying SongSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, ChinaWeifang WangSchool of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, ChinaZhen JiaoCentre for Nanobiotechnology, Joint Research Institute of Southeast University and Monash University, Suzhou 215123, China

2018en

ABI

Аннотация

Vitamin E acetate (VEA) has been widely used as medicines, nutrients, and cosmetic additives. Solubility data are generally used to aid the design of processes to prepare products that provide the required dosage of the active compound(s). In this study, the static cloud-point method is employed to determine the solubility of VEA in supercritical carbon dioxide (scCO2) with ethanol (0.5, 1.0, and 2.0 mol %) as the cosolvent at temperatures of 313.15, 318.15, 323.15, and 328.15 K, and pressures of 8–15 MPa. The results show that the solubility of VEA in scCO2 can be remarkably enhanced by adding ethanol as the cosolvent. It could also be increased with the enhancing pressure and the decreasing temperature at the constant ethanol concentration. Furthermore, some semiempirical models including Christil-G, K-J, Bartle, MST-S, Reddy, and Pérez are employed to correlate the experimental data. The average absolute relative deviations values of these models range from 2.43 to 6.86%, indicating that these models could well predict the VEA solubility data in scCO2 + ethanol systems of this study.

Ҳали таржима қилинмаган

Идентификаторлар

DOI: 10.1021/acs.jced.8b00745

Иқтибослар ва манбалар

2 та иқтибос0 та фойдаланилган манба

Кўрсаткичлар — AkademScholar