Targeted protein degradation via the autophagy-lysosome system: AUTOTAC (AUTOphagy-TArgeting Chimera)
Chang Hoon JiCellular Degradation Biology Center, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, KoreaMin Ju LeeCellular Degradation Biology Center, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, KoreaHee Yeon KimCellular Degradation Biology Center, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, KoreaAh Jung HeoCellular Degradation Biology Center, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, KoreaDaniel Youngjae ParkCellular Degradation Biology Center, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, KoreaYun Kyung KimConvergence Research Center for Brain Science, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, KoreaBo Yeon KimChemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongju, KoreaYong Tae KwonCellular Degradation Biology Center, Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Korea
2022en
ABI
Аннотация
. We suggest that AUTOTAC provides a platform for selective proteolysis as a research tool and in drug development.
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