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Stairway Plot 2: demographic history inference with folded SNP frequency spectra

Xiaoming LiuUSF Genomics & College of Public Health, University of South Florida, Tampa, FL, USA. [email protected]Yun‐Xin FuDepartment of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA
2020en
ABI

Аннотация

Inferring the demographic histories of populations has wide applications in population, ecological, and conservation genomics. We present Stairway Plot 2, a cross-platform program package for this task using SNP frequency spectra. It is based on a nonparametric method with the capability of handling folded SNP frequency spectra (that is, when the ancestral alleles of the SNPs are unknown) of thousands of samples produced with genotyping-by-sequencing technologies; therefore, it is particularly suitable for nonmodel organisms.

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