Asymmetric Total Synthesis of the Proposed Structure of the Medicinal Alkaloid Jamtine Using the Chiral Base Approach

[reaction: see text] A highly step-economic asymmetric synthesis of the tetracyclic structure assigned to the medicinal alkaloid jamtine has been accomplished using a chiral lithium amide base desymmetrization of a ring-fused imide. The structure synthesized appears to be different from that of the natural product originally reported.

Ҳали таржима қилинмаган