Мақола

Studies on the Constituents of Cimicifuga Species. XIX. Eight New Glycosides from Cimicifuga simplex WORMSK.

Akiko KusanoOsaka University of Pharmaceutical Sciences, JapanMakio ShibanoOsaka University of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences, School of Pharmaceutical Sciences, University of Shizuoka, Osaka University of Pharmaceutical SciencesGenjiro KusanoOsaka University of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences, School of Pharmaceutical Sciences, University of Shizuoka, Osaka University of Pharmaceutical SciencesToshio MiyaseOsaka University of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences, School of Pharmaceutical Sciences, University of Shizuoka, Osaka University of Pharmaceutical Sciences

1996en

ABI

Аннотация

Eight new glycosides were isolated from Cimicifuga simplex (Ranunculaceae), and their structures were determined to be 23-O-acetyl-7-8-didehydroshengmanol-3-O-alpha-L-arabinopyranosi de (1), 24-epi-24-O-acetyl-7,-8- didehydrohydroshengmanol-3-O-beta-D-galactopyranoside (2), 7,8-didehydrocimigenol-3-O-beta-D-galacytopyranoside (3), 24-epi-24-O-acetylhydroshengmanol-3-O-beta-D-galactopyranoside (4), cimigenol-3-O-beta-D-galactopyranoside (5), 25-O-methylcimigenol-3-O-beta-D-galactopyranoside (6), 25-O-acetylcimigenol-3-O-beta-D-galactopyranoside (7) and 25-O-acetylcimigenol-3-O-beta-D-glucopyranoside (8). Genuine aglycones were obtained by the hydrolysis of 1--7 with lactase F[Amano] and of 8 with cellulase T[amano]4. Acerinol was prepared from 7,8-didehydrocimigenol and showed antilipemic effects.

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Идентификаторлар

DOI: 10.1248/cpb.44.2078

Иқтибослар ва манбалар

8 та иқтибос0 та фойдаланилган манба

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