MORPHOLOGICAL EFFECTS OF VITAMIN D DEFICIENCY ON BONE TISSUE: OSTEOPOROSIS AND OSTEOMALACIA

Vitamin D is an important endocrine regulator that controls bone metabolism. Its deficiency leads to disruption of calcium-phosphorus homeostasis, imbalance of osteoblast and osteoclast activity, and disruption of bone microarchitecture. This article analyzes the morphological changes caused by vitamin D deficiency in bone tissue, in particular its role in the pathogenesis of osteoporosis and osteomalacia, at the histological and ultrastructural levels.

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