LIDDLE SYNDROME: PATHOPHYSIOLOGY, CLINICAL FEATURES, TREATMENT.

Liddle syndrome is a rare autosomal dominant disorder characterized by early-onset hypertension, hypokalemia, and metabolic alkalosis. It results from gain-of-function mutations in epithelial sodium channel (ENaC) subunits. This expanded review covers detailed molecular mechanisms, clinical manifestations, diagnostics, differential diagnosis, and modern treatment approaches.

Ҳали таржима қилинмаган