Nuclear bone imaging in metastatic cancer of the prostate
Jeffrey J. PollenAssistant Professor in Residence, Department of Surgery, Division of UrologyKenneth GerberResident, Department of Radiology, Division of Nuclear MedicineWilliam L. AshburnProfessor of Radiology and Head, Division of Nuclear MedicineJoseph D. SchmidtUniversity of California Medical Center, San Diego, California
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A reproducible technique of bone scanning in prostatic cancer is described that helps ensure the production of successive studies of highly comparable technical quality. Through an analysis of survival data based on changes in distribution, anatomic extent, and intensity of bone scan abnormalities in patients with advanced prostatic cancer, it is demonstrated that alterations in the appearance of the bone scan correlate closely with disease activity and have great prognostic significance.
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