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Aplastic anemia induced by cyclohexylchloroethylnitrousurea

Avishay ElisDepartment of Medicine, Sackler Faculty of Medicine, Tel Aviv University and Meir Hospital, Kfar Saba 44281, Israel. Tel: (+972) 9 900 534Michael LishnerInstitute of Nuclear PhysicsH SavinInstitute of Nuclear PhysicsMordchai RavidInstitute of Nuclear Physics
Anti-Cancer Drugsjournal1994en

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We report a patient who developed aplastic anemia after three courses of cyclohexylchloroethylnitrousurea (CCNU), procarbazine and oncovine administered after craniotomy and irradiation for brain astrocytoma. To the best of our knowledge, aplastic anemia following CCNU has not been reported previously. The unique course of the disease and implications of this complication are discussed.

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