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EXPERIMENTAL STUDIES OF THE INFLUENCE OF MIX OF THE CALCIUM AND MAGNESIUM SALTS OF INOSITOLHEXAPHOSPHATE ACID ON BILIATION FUNCTION OF A LIVER AT THE ACUTE HEPATITIS

Z. Z. Khakimov2<SUP>nd</SUP> Tashkent State Medical Institute, Pharmacology DepartmentS. S. KASIMOVA2<SUP>nd</SUP> Tashkent State Medical Institute, Pharmacology DepartmentB. M. ASCAMOV2<SUP>nd</SUP> Tashkent State Medical Institute, Pharmacology DepartmentJ. Z. AKRAMOVA2<SUP>nd</SUP> Tashkent State Medical Institute, Pharmacology Department
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For white pubertal male-rats was reproduced the model of acute necrosis a hepatitis by way of hypodermic inoculation of the acetothioamide and investigated the influencing a mix of calcium and magnesium salts of the inositolhexaphosphate acid on the excretive function of a liver and elemental composition of bile. It is established that the mix of salts of the inositolhexaphosphate acid at an acute hepatitis is remove considerable disturbance on excretive function of a liver and elemental composition of bile. The studied compound has a cholagogic, hypobilirubinic and hepatoprotective properties and present the important interest as a drug for treatment of acute and chronic defects of a liver.

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