Получение микрокапсул на основе яблочного пектина и β-лактоглобулина, содержащих рифампицин

A two-stage technology of rifampicin-containing microcapsules based on high- and low-methylated apple pectin complexes with milk serum β-lactoglobulin has been developed using an oil-water emulsion system. It is established that the ability of pectin chains to form an effective secondary layer on protein molecules surrounding oil drops depends on the molecular weight and structure of pectin. The obtained emulsion systems with two pectins and various pectin/protein ratios are capable of forming microcapsules with various dimensions and different rifampicin content. The proposed microcapsules can be used as potential drug carriers.

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