Lipid fractions from Scutellaria ramosissima tested on the microtubular array of cancer cell models
Nilufar Z. MamadalievaInstitute of the Chemistry of Plant Substances AS RUz, MirzoUlugbek Str. 77, Tashkent 100170Elisa OvidiDepartment for the Innovation in Biological, Agro-food and Forestal systems, Laboratory of Plant Cytology and Biotechnology, Tuscia UniversityDoriana TriggianiDepartment for the Innovation in Biological, Agro-food and Forestal systems, Laboratory of Plant Cytology and Biotechnology, Tuscia UniversityYuldasheva, Nigora K.Institute of the Chemistry of Plant Substances AS RUz, MirzoUlugbek Str. 77, Tashkent 100170Ulchenko, Natalya T.Institute of the Chemistry of Plant Substances AS RUz, MirzoUlugbek Str. 77, Tashkent 100170Anna I. GlushenkovaInstitute of the Chemistry of Plant Substances AS RUz, MirzoUlugbek Str. 77, Tashkent 100170Antonio Tiezziuniversità degli Studi della Tuscia
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Scutellaria ramosissima (Lamiaceae) is a plant used in traditional Uzbek medicine for cancer and inflammatory therapy. The aim of this work is to investigate the microtubular component of the HeLa and HL-60 cells cytoskeleton after treatment with the isolated lipid fractions from S. ramosissima by using immunofluorescence analysis. In our hands a relation between the administration of isolated lipid fractions and the microtubule array did not occur. Our data confirmed that the microtubular cytoskeleton is not the cytoplasmic target of molecules consisting the lipid fractions from Scutellaria ramosissima .
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