Maqola

DESIGN AND CHARACTERIZATION OF A DESK-TOP LASER PLASMA X-RAY SOURCE FOR RADIOBIOLOGY STUDIES

Daniel AdjeiInstitute of Optoelectronics, Military University of Technology, Warsaw, PolandA. WiechećInstitute of Nuclear Physics , Polish Academy of Sciences , Cracow , PolandP. WachulakInstitute of Optoelectronics , Military University of Technology , Warsaw , PolandMesfin Getachew AyeleInstitute of Optoelectronics , Military University of Technology , Warsaw , PolandJanusz LekkiPolish Academy of SciencesWojciech M. KwiatekInstitute of Nuclear Physics , Polish Academy of Sciences , Cracow , PolandAndrzej BartnikInstitute of Optoelectronics , Military University of Technology , Warsaw , PolandL. Pı́naFaculty of Nuclear Sciences and Engineering Physics , Czech Technical University in Prague , Prague , Czech RepublicHenryk FiedorowiczInstitute of Optoelectronics , Military University of Technology , Warsaw , Poland

2016en

Ochiq kirishBronza

ABI

Annotatsiya

A compact desk-top laser-produced plasma source of soft X-rays for radiobiology research is presented.The source is based on a double-stream gas puff target and delivers nanosecond pulses of soft X-rays in the "water window" spectral range at a fluence of about 4.23×10 3 photon/µm 2 per pulse on a sample placed inside the vacuum source chamber and about 2.60×10 2 photon/µm 2 per pulse on a wet sample located outside the chamber in the Heenvironment.The source has been used to irradiate pBR322 plasmid DNA both in vacuum and the He-environment conditions.Single and double strand breaks were quantified by gel electrophoresis.The number of strand breaks increased with the increasing dose of the "water window" soft X-rays.The strand breaks of plasmid solution irradiated in helium condition may be associated with damage from water-free radicals.

Hali tarjima qilinmagan

Identifikatorlar

DOI: 10.21175/radj.2016.02.016

Iqtiboslar va manbalar

0 ta iqtibos26 ta foydalanilgan manba