STUDY OF THE STRUCTURAL AND FUNCTIONAL STATE OF THE MYOCARDIUM IN WOMEN WITH ARTERIAL HYPERTENSION IN PERIMENOPAUSE

In present work the correlation between parameters of endothelium dysfunction within various climacterium stages features functioning of remodeling heart vessels were discovered.It is proved that correction hormonal disorders of women in perimenopause with moderate risk of cardiovascular complications, stabilization of endothelium function by selective modulators of estrogen receptors -of Klimadinon for 12 weeks in doze of 40 mg allows to reach restoration of endothelium function and to stabilize the level of blood pressure.Efficiency of 12 weeks combined therapy klimadinon and hypotensive therapies (moxonidin) is proved, concerning achievement of target level of blood pressure, improvements of parameters recourse of remodeling hearts and vessels at women in climacterium with arterial hypertension I and II degrees.

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