GENETIC THROMBOPHILIA COMPLICATED BY VARICOSE VEIN THROMBOSIS AND THROPHIC ULCERS – A CLINICAL CASE REPORT

Genetic factor is the leading in the development of varicose veins, although certain risk factors, including: overweight, old age, female gender, sedentary lifestyle, lower limb trauma and others contribute to its formation. Thrombophilia is a risk factor for the development of venous thrombosis and chronic recurrent trophic ulcer, although the relationship between them is not well understood. Hereditary thrombophilia is a rare disease characterized by severe complications. The correlation between thrombophilia, varicose veins, and chronic venous ulceration is quite strong. This paper describes the case of a 43-year-old man who was treated in the intensive care unit of the clinic in July 2019 with the diagnosis: thromboembolism of the pulmonary artery, thrombophilia, phlebitis and thrombosis in the phase of recanalization, with chronic venous insufficiency of the lower limbs, with a long history of varicose veins of both limbs and with diabetes mellitus. Faced complaints were: easy fatigue, weakness, shortness of breath, heart palpitations, feeling of heaviness and pain in the lower limbs, swelling. In the anamnesis - several cases of exacerbation of superficial vein thrombophlebitis were present. Despite the uncertain prognosis, remission was achieved on the background of intensive anticoagulation therapy. Considering recurrent thrombophlebitis, screening was prescribed. The case is interesting from both a theoretical and a practical point of view, since the described severe process became manageable - the acute form was transformed into a chronic one with a long remission. At this stage, the disease is not progressing, there are no additional complications.

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