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Synthesis and characterization of manganese-L-arginine framework (MOF) for antibacterial and antioxidant studies

M KiranDepartment of Chemistry , University of Azad Jammu and Kashmir , Muzaffarabad 13100 , PakistanKh. A. YasinS. HaqDepartment of Chemistry , University of Azad Jammu and Kashmir , Muzaffarabad 13100 , PakistanKh. ElmnasriM. Ben AliFehmi BoufahjaBiology Department , College of Science , Imam Mohammad Ibn Saud Islamic University (IMSIU) , P.O. Box 90950 , Riyadh 11623 , Saudi ArabiaO. ShukurovInstitute of Material Sciences , Academy of Sciences , Chingiz Aytmatov 2b , 100084 Tashkent , UzbekistanEbrahim MahmoudiCoastal Ecology and Ecotoxicology Unit , Laboratory of Environment Biomonitoring , Faculty of Sciences of Bizerte , University of Carthage , Zarzouna 7021 , TunisiaAmor HedfiDepartment of Biology , College of Sciences , Taif University , P.O. Box 11099 , Taif , 21944 , Saudi Arabia
2024en
ABI

Annotatsiya

Due to their unique properties, metal-organic frameworks (MOF-2) have demonstrated significant potential for various biomedical applications. In this research, a manganese-Larginine framework (MOF-2) was synthesized and characterized using techniques such as X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The MOF-2's antibacterial activity against selected bacteria was evaluated via the agar-well diffusion method, and it was found to be more effective against E. coli than S. aureus. Furthermore, the MOF-2's potential as an antioxidant was investigated using the spectrophotometric method against ABTS and DPPH free radicals, with the MOF-2 displaying higher antioxidant activity against DPPH. The obtained results indicate that the synthesized MOF-2 possesses potent antibacterial and antioxidant activities, making it a promising candidate for various biomedical applications.

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