DEVELOPMENT OF TECHNOLOGY FOR PRODUCING A TINCTURE WITH A SEDATIVE EFFECT

The purpose of this work was to experimentally select the optimal conditions for obtaining a tincture with a sedative effect, consisting of a mixture of motherwort herbs, lemon balm and stinging nettle leaves in a ratio (1 : 1 : 1), and to develop quality criteria for the finished product. The influence of extractant concentration, ratio of raw materials and extractant, extraction frequency and infusion mode using auxiliary technologies (ultrasonic treatment) on the yield of biologically active substances from plant raw materials was studied. When developing a method for producing a tincture with a sedative effect, consisting of a mixture of motherwort herbs, lemon balm and stinging nettle leaves, based on the quantitative content of flavonoids in terms of rutin, it was established that the most acceptable method of production is maceration using ultrasound, the optimal extractant is 70% ethyl alcohol. Based on the results obtained regarding the influence of the degree of grinding of raw materials on the yield of flavonoids from medicinal plant raw materials, our choice was made on a size of 1–3 mm and a ratio of raw materials to extractant of 1 : 10. This method allows you to obtain a tincture with a high yield of flavonoids with the least amount of time.

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