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Polyphenols from Cydonia oblonga Miller leaves: Extraction, characterization, and biological activities

Sakhiba MadrakhimovaInstitute of Bioorganic Chemistry named after. acad. A.S. Sadykova Academy of Sciences of the Republic of Uzbekistan , st. Mirzo Ulugbek , 83 , Tashkent , 100125 , Republic of UzbekistanBakhtishod MatmuratovYu. T. YunuskhujaMaxliyo JumaniyazovaInstitute of Bioorganic Chemistry named after. acad. A.S. Sadykova Academy of Sciences of the Republic of Uzbekistan , st. Mirzo Ulugbek , 83 , Tashkent , 100125 , Republic of UzbekistanUlugbek TogaevInstitute of Bioorganic Chemistry named after. acad. A.S. Sadykova Academy of Sciences of the Republic of Uzbekistan , st. Mirzo Ulugbek , 83 , Tashkent , 100125 , Republic of UzbekistanAlimzhan Davlatbaevich MatchanovInstitute of Bioorganic Chemistry named after. acad. A.S. Sadykova Academy of Sciences of the Republic of Uzbekistan , st. Mirzo Ulugbek , 83 , Tashkent , 100125 , Republic of Uzbekistan
2025en
ABI

Annotatsiya

We extracted the leaves of Cydonia oblonga Miller and qualitative reactions specific to total polyphenols were performed on the leaves with certain reagents.An aqueous extract of the plant leaf turned a solution of FeCl 3 green, a qualitative reaction to an aromatic ring.We observed a color change from orange to light red when we experimented with a 1% vanillin solution in hydrochloric acid.This reaction is characteristic of condensed polyphenols; namely, anthocyanidins (catechins).Total polyphenols were isolated from C. oblonga leaves using extraction methods and organic solvents (acetone, chloroform, ethyl acetate), known in the literature.Studies were conducted to investigate the medicinal properties of an extract isolated from the leaves of C. oblonga on the mitochondrial membrane status of mouse cells.An extract isolated from the leaves of C. oblonga showed antioxidant and membrane-active properties and had a corrective effect on the state of the mitochondrial membrane.It can be concluded that the substances extracted from C. oblonga leaves are highly biologically active substances.

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