Menthosomes: A Comprehensive Review

Menthosomes represent an innovative class of nanocarriers that combine menthol with lipid based vesicles, typically phospholipids, to improve the delivery of therapeutic agents. The inclusion of menthol enhances the permeability of the skin and mucous membranes, making these carriers highly effective for transdermal and mucosal drug delivery. This review provides an in-depth examination of menthosomes, discussing their composition, preparation methods, and the mechanisms by which they enhance drug absorption and stability. Furthermore, it highlights the role of menthol in improving the bioavailability, solubility, and controlled release of encapsulated compounds. The review also explores the broad potential applications of menthosomes in pharmaceutical and cosmetic industries, while identifying current challenges and suggesting future avenues for their development and optimization in drug delivery systems.

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