SERUM INFLAMMATORY, IMMUNOREGULATORY, AND REPAIR ASSOCIATED PROFILES IN INFILTRATIVE CUTANEOUS LEISHMANIASIS: A COMPARATIVE ANALYSIS OF PROBABLE ZOONOTIC AND ANTHROPONOTIC TYPES
Aripova Tamara UktamovnaInstitute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Republic of UzbekistanBoyqobilov Soatmurod Shukhrat ugliTermez University of Economics and Services, Termez, Republic of UzbekistanSaipova Nodira SagdullayevnaMedical State Medical University, Tashkent, Republic of UzbekistanZukhra S. AzizovaMedical State Medical University, Tashkent, Republic of UzbekistanRuzimurodov Nodir FazliddinovichMedical State Medical University, Tashkent, Republic of Uzbekistan
2025en
Ochiq kirishOlmos
Litsenziya: cc-by
ABI
Annotatsiya
Background. Cutaneous leishmaniasis (CL) is characterized by heterogeneous inflammatory responses and variable patterns of tissue involvement. The relationship between systemic inflammatory mediators, immunoregulatory cytokines, and repair-associated growth factors across different clinical and epidemiological presentations remains insufficiently characterized.Objective. To compare serum inflammatory, immunoregulatory, and repair-associated biomarkers in patients with infiltrative CL classified as having probable zoonotic or probable anthroponotic disease.
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