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Are Antibiotic Prescribing Patterns for Endodontic Infections Among Undergraduate Dental Students Consistent With Current Guidelines? A Multinational Cross‐Sectional Study

Mohamed Ahmed ElsayedDepartment of Endodontics, Faculty of Dentistry Assiut University Assiut EgyptFatma Pertek HatipoğluDepartment of Endodontics Recep Tayyip Erdoğan University Rize TürkiyeNessrin TahaDepartment of Conservative Dentistry Jordan University of Science and Technology Irbid JordanMohideen Salihu FarookDepartment of Restorative Dentistry, Faculty of Dentistry Universiti Malaya Kuala Lumpur MalaysiaSaaid Al ShehadatDepartment of Restorative Dentistry, College of Dental Medicine University of Sharjah Sharjah UAERafael Fernández‐GrisalesDepartment of Endodontics, School of Dentistry CES University Medellín ColombiaDaoud Mahmoud AyyadDepartment of Endodontics, Faculty of Dentistry Al‐Quds University East Jerusalem PalestineBekjanova Olga YesenovnaDepartment of Therapeutic Dentistry Tashkent State Medical University Tashkent UzbekistanBakhyt A. OmarovaDepartment of Orthodontics S.D. Asfendiyarov Kazakh National Medical University, School of Dentistry Almaty KazakhstanMohmed Isaqali KarobariDepartment of Conservative Dentistry and Endodontics Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai IndiaNovaldy WahjudiantoDepartment of Conservative Dentistry, Faculty of Dental Medicine Universitas Airlangga Surabaya IndonesiaMartha E. GallegosDepartment of Endodontics, Faculty of Dentistry Universidad Central del Ecuador Quito EcuadorNawar Naguib NawarDepartment of Endodontics The British University in Egypt Cairo EgyptAhmed A. MadfaDepartment of Restorative Dental Science, College of Dentistry University of Ha'il Ha'il Saudi ArabiaAnna LehmannDepartment of Conservative Dentistry Poznań University of Medical Sciences Poznań PolandThiyezen Abdullah AldhelaiBuraydah CollegesJosé Martín‐CrucesDepartment of Operative Dentistry University of Santiago de Compostela Santiago de Compostela SpainNiher Tabassum SnigdhaDepartment of Dental Research, Saveetha Medical College and Hospital Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai IndiaPaulo PalmaCenter for Innovation and Research in Oral Sciences (CIROS) and Institute of Endodontics, Faculty of Medicine University of Coimbra Coimbra PortugalDavid DonnermeyerDepartment of Restorative, Preventive and Pediatric Dentistry, School of Dental Medicine University of Bern Bern SwitzerlandO N HatipogluDepartment of Restorative Dentistry, Faculty of Dentistry Recep Tayyip Erdoğan University Rize Türkiye
2026en
ABI

Annotatsiya

AIM: Appropriate antibiotic prescribing is a core competency in dental education. This study evaluated dental students' knowledge, antibiotic selection patterns, and adherence to international guidelines for the management of endodontic infections. MATERIALS AND METHODS: An online survey was administered to students in their final two clinical years across 19 countries. Three clinical scenarios were evaluated: first-line antibiotic choice, second-line when the first choice is ineffective, and drug of choice for penicillin-allergic patients. Participants reported drug, dose, frequency, and duration. Guideline adherence was quantified using a 0-5 scoring system based on European Society of Endodontology and American Association of Endodontists recommendations. Mixed-effects linear regression models with country as a random effect were used to identify predictors of guideline-concordant prescribing. RESULTS: A total of 4226 responses were analysed. Amoxicillin was the most frequently selected first-line antibiotic (57.6%), followed by amoxicillin-clavulanic acid (18.4%), with marked between-country variation; adjusted first-choice concordance was highest in Colombia (4.57) and lowest in Bangladesh (2.49). For second-line therapy, amoxicillin-clavulanic acid predominated (33.2%), with the highest adherence in Ecuador (3.40) and the lowest in Switzerland (2.15). In penicillin-allergic patients, clindamycin was most commonly selected (47.8%), but allergy-specific concordance varied widely, ranging from 3.52 in Colombia to 1.06 in India. Age positively predicted second-line concordance, while lower allergy-specific concordance was observed among second-year students and males. CONCLUSIONS: Marked variability and frequent deviations from guideline-recommended prescribing highlight persistent educational gaps. Strengthening antimicrobial stewardship training within undergraduate dental curricula is warranted.

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