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EARLY OUTCOMES OF LIVING-RELATED DONOR KIDNEY TRANSPLANTATION WITH MULTIPLE RENAL ARTERIES: A RETROSPECTIVE COHORT STUDY WITH AN MSCT-GUIDED ARTERIAL RECONSTRUCTION FRAMEWORK

A SuyumovState Institution “Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov”, Tashkent, UzbekistanZ. T. MatkarimovTashkent Pediatric Medical InstituteМузаффар Олимжон угли РустамовTashkent Pediatric Medical InstituteD KomilovaState Institution “Republican Specialized Scientific and Practical Medical Center of Surgery named after Academician V. Vakhidov”, Tashkent, Uzbekistan
2026

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Annotatsiya

Multiple renal arteries increase the technical complexity of living-donor kidney transplantation. This retrospective single-center cohort compared fixed-time outcomes in 578 living-related donor kidney transplantations: 471 grafts had one renal artery and 107 had two or more. All donors underwent preoperative multislice computed tomography angiography with three-dimensional reconstruction, and reconstruction was individualized according to vascular anatomy. Because outcome events were sparse, two-sided Fisher exact tests and absolute differences in survival proportions with 95% confidence intervals were used. Multiple-artery grafts accounted for 18.5% of the cohort, and 101 of 107 had two arteries. Six-month graft survival was 97.9% for single-artery grafts and 97.2% for multiple-artery grafts (difference, -0.7 percentage points; 95% CI [-5.9, 1.9]; p = .716). Twelve-month graft survival was 96.2% and 96.3%, respectively (difference, 0.1 percentage points; 95% CI [-5.6, 3.2]; p = 1.000). Recipient survival showed no statistically detectable difference at 6 months (96.8% vs. 96.3%; p = .765) or 12 months (95.5% vs. 94.4%; p = .613). These unadjusted analyses do not establish equivalence or noninferiority. Selected multiple-artery living-donor grafts were feasible in this experienced center, but the proposed MSCT-guided planning framework and area-equivalent ostial diameter remain descriptive tools requiring further validation.

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