CURRENT PERSPECTIVES AND CONTROVERSIAL EVIDENCE ON THE IMPACT OF NORMOBARIC HYPEROXYGENATION ON BRAIN MORPHOLOGY: A LITERATURE REVIEW

Resume. In this literature review, the effect of normobaric hyperoxygenation (NBHO) on the morphological state of brain tissues is analyzed. In the study, along with the neuroprotective properties of NBHO, scientific contradictions between destructive changes that may occur as a result of free radical activation are considered. Based on various experimental and clinical data, the effect of an oxygen-enriched environment on the processes of neuronal regeneration and apoptosis is comparatively studied. The results of the article serve as an important theoretical basis in determining the therapeutic limits of NBHO and preventing neuromorphological complications. Keywords: Normobaric hyperoxygenation (NBHO), brain morphology, neuroprotection, oxidative stress, neuronal destruction, hypoxia.

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