Bolalardagi oʻtkirosti sklerozlanuvchi panensefalit (SSPE): klinik kechishi, tashxis va palliativ yondashuvlar
Litsenziya: cc-by
Annotatsiya
Subacute sclerosing panencephalitis (SSPE) is a chronic, progressive neurodegenerative disorder resulting from the prolonged persistence of the measles virus within the central nervous system. It primarily affects children and adolescents and is clinically characterized by cognitive decline, myoclonic seizures, extrapyramidal signs, and eventual progression to a vegetative state. This article discusses the epidemiology, etiopathogenesis, clinical stages, diagnostic criteria, available antiviral agents, and immunomodulatory therapy options, as well as stage-specific palliative and rehabilitative approaches. The role of multidisciplinary palliative care and vaccination in preventing SSPE and improving patients’ quality of life is emphasized.