Immunizatsiya qilingan tajriba quyon modelida brutsellyoz ta’sirida buyrakdagi patomorfologik o‘zgarishlar
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Annotatsiya
This study investigated pathomorphological changes in kidney tissue under the influence of brucellosis infection in an immunized experimental rabbit model. During the experiment, rabbits weighing 3.0–3.5 kg were selected and immunized according to a predetermined scheme. Subsequently, the histological structure of the kidney tissue was examined microscopically using the hematoxylin–eosin staining method. The results revealed inflammatory processes in the renal parenchyma, lymphohistiocytic infiltration, hyperemia of blood vessels, and microgranulomatous changes in certain areas. In addition, dystrophic alterations in the epithelium of the renal tubules and the accumulation of immune cells in the interstitial tissue were observed, indicating immunobiological reactions occurring in the organism under the influence of infection. The obtained pathomorphological findings are of significant scientific and practical importance for evaluating the effects of brucellosis infection on kidney tissue and for a deeper understanding of the pathogenesis of the disease.