TIZIMLI QIZIL BO’RICHADA NEVROLOGIK O’ZGARISHLAR: ZARARLANISH SPEKTRI, PATOGENEZI, DIAGNOSTIKA VA DAVOLASH YONDASHUVI. (Adabiyotlar sharxi)

Annotatsiya

Neurological manifestations in systemic lupus erythematosus (SLE) represent one of the most common and clinically significant complications of the disease, reflecting involvement of both the central and peripheral nervous systems. These manifestations encompass a wide spectrum of symptoms, ranging from cognitive impairment and seizures to cerebrovascular and psychiatric disorders. The pathogenesis is multifactorial and involves autoimmune inflammation, vasculopathy, and thrombotic mechanisms [3,4]. Diagnosis requires a comprehensive approach integrating clinical, instrumental, and laboratory methods. Treatment is based on the underlying pathogenic mechanisms and includes both immunosuppressive and symptomatic therapies [2,11].

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