COMPONENTS OF THE AERIAL PART OF SALVIA SARAWSCHANICA

The component composition of the essential oil (EO) obtained by hydrodistillation from the air-dried aboveground part of Salvia sarawschanica Regel et Schmalh collected during the flowering period in the Navoi region of the Republic of Uzbekistan was studied. Using GC-MS, 36 compounds were identified in the essential oil from the air-dried aboveground part, which accounted for 95.1% of the total oil. Oxidized monoterpenes (41.5%) and monoterpenes (32.7%) predominate in the composition of EO. Sesquiterpenes account for 10.3% of EO, oxidized sesquiterpenes were not detected. The main components of EO are 1,8-cineole, camphene, camphor, aromadendrene and limonene, the content of which was 33.8, 12.3, 6.8, 5.2 and 4.9%, respectively. The aerial part of S. sarawschanica can serve as a rich source of 1,8-cineole. Three individual phenolic compounds were isolated from different fractions of 80% ethanol extract of S. sarawschanica roots, which were identified with acacetin, luteolin, cynaroside, luteolin-3'-O-β-D-glucuronide, β-sitosterol and stigmasterol based on 1H, 13C NMR, HSQC and HMBC spectra. The antibacterial and antifungal activity of essential oil extracts, benzene and ethyl acetate extracts of the aerial part of S. sarawschanica was studied by the disk diffusion method in agar. The test results showed that the EO oil from the above-ground parts of the plant S. sarawschanica exhibits a noticeable antibacterial effect against the gram-positive strain of bacteria B. subtilis.

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