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One Electrifying Decade of Organic Syntheses: A Literature Survey Based on Different Electrode Combinations

Vaishali VaishaliDepartment of Applied Sciences and Humanities (Chemistry), Galgotias College of Engineering and Technology, Knowledge Park II, Greater Noida 201310, Uttar Pradesh, IndiaShubham SharmaOrganic Synthesis Research Laboratory, Department of Chemistry, GLA University, 17 km Stone, NH-19, Mathura-Delhi Road, Chaumuhan, Bharthia 281406, Uttar Pradesh, IndiaNozimjon TukhtaboevKokand State Pedagogical Institute named after MukimiBobur MirzayevDepartment of Finance, Alfraganus University, Tashkent 100190, UzbekistanHimansh KumarMechanical Engineering Department, Teerthanker Mahaveer University, Moradabad 244001, Uttar Pradesh, IndiaAaysha PandeyAshish GaurDepartment of Biosciences, Graphic Era (Deemed to be) University, Dehradun 248002, Uttarakhand, IndiaNaresh Kumar WagriDepartment of Materials Science and Engineering, KTH Royal Institute of Technology, SE-10044 Stockholm, SwedenSobhi M. GomhaDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah 42351, Saudi Arabia

2026en

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Synthetic organic chemistry offers an endless scope in various domains of science, and electro-organic synthesis has grown as a green alternative to synthetic organic chemistry, obviating the necessity for harmful oxidants and reductants. Electro-organic reactions have attracted considerable attention globally in both academia and industry. This study analyzes the electrochemical organic synthesis towards the synthesis of valuable organic compounds. Electro-organic methodologies encompass C—P/C—O/C—N/N—N bond formation, C—H/N—H functionalization, C—N/C—S cross—coupling, ring expansion, oxidation dearomatization/annulation, C—H thiolation, dehydrogenative C(sp2)—H amination, C(sp3)—H/C(sp2)—H functionalization, sulfur insertion, Henry reaction, and Buchwald–Hartwig amination. This review emphasizes the synthesis of diversified organic compounds that possess remarkable biological features and show considerable potential in medicinal chemistry. The current review summarizes the reports from the recent decade that represent electro-organic synthesis for the development of diversified organic compounds.

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DOI: 10.3390/catal16100911

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