Advancements In Non-Invasive Skin Tightening Procedures: Combining Dermatologic And Surgical Modalities

Background: Non-invasive skin tightening procedures have become increasingly popular for the management of agerelated skin laxity because they provide aesthetic improvement with minimal downtime and reduced procedural risk. Objective: To evaluate the efficacy and safety of combined non-invasive skin tightening procedures and identify factors associated with successful treatment outcomes. Methods: This retrospective observational study was conducted at Burn and plastic surgery center Hayatabad from April 2024 to April 2025 and included 190 patients who underwent non-invasive skin tightening using single or combination treatment modalities. Results: The mean age of patients was 46.7 ± 9.8 years, and 142 (74.7%) were female. Combination therapy was performed in 89 (46.8%) patients, while 101 (53.2%) received single-modality treatment. Significant improvements were observed in GAIS (1.4 ± 0.5 to 3.8 ± 0.7), WSRS (3.6 ± 0.7 to 2.1 ± 0.6), skin elasticity (42.5 ± 8.4 to 61.8 ± 9.6), physician global assessment (2.1 ± 0.6 to 4.0 ± 0.7), and patient satisfaction (54.6 ± 13.2% to 86.4 ± 10.5%) (all p<0.001). Overall successful treatment was achieved in 151 (79.5%) patients. Conclusion: Combined non-invasive dermatologic and minimally invasive skin tightening modalities provide significant aesthetic improvement with excellent safety and high patient satisfaction. Younger age, lower body mass index, absence of smoking, milder skin laxity, and combination therapy are associated with superior treatment outcomes.

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