THE STUDY OF BIOEQUIVALENCE (ACUTE TOXICITY AND ANTITHROMBOTIC ACTIVITY) TABLETS «PASCOR»
Bakhtiyor Alisherovich ImamalievShokhid GulyamovState Institution "Center for Pharmaceutical Products Safety" under the Ministry of Health of the Republic of UzbekistanState Institution "Center for Pharmaceutical Products Safety" under the Ministry of Health of the Republic of Uzbekistan
2026ru
ABI
Annotatsiya
The bioequivalence of the preparation «Pascor» coated tablets 150 мг/30,4 мг, production: FC LLC «Nobel Pharmsanoat» Uzbekistan, in comparison with the preparation «Cardiomagnil» coated tablets 150 мг/30,4 мг, production: «Takeda GmbH» Germany, was studied in terms of acute toxicity and antithrombotic activity.The study of acute toxicity was carried out according to generally accepted method. The antithrombotic activity of the preparation was studied on the model of generalized adrenaline-collagen thrombosis in mice..As a result, it was found that the test preparation is bioequivalent to the reference preparation. Key words: antiaggregants, acute toxicity, antithrombotic activity, acetylsalicylic acid.
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