Maqola

Interfacial engineering of silver quantum dots for antibacterial applications: From surface chemistry to translational design

Chou-Yi HsuHajar khaled MasserDepartment of Anesthesia Techniques, College of Health and Medical Technology, University of Al Maarif, Al Anbar, 31001, IraqMirza R. BaigI.B. SapaevSchool of Engineering, Central Asian University, Tashkent, 111221, UzbekistanRekha M. MDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed-to-be University), Bangalore, Karnataka, IndiaHarvinder Singh SohalDepartment of Chemistry, University Institute of Sciences, Chandigarh University, Mohali, Punjab, IndiaVibha JoshiDepartment of Chemistry, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, IndiaRahul SaxenaDepartment of Biochemistry, Sharda University, Knowledge Park III, Greater Noida, IndiaAseel SmeratDepartment of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai 602105, IndiaHadi NoorizadehElite Club, Tehran Branch, Islamic Azad University, Tehran, Iran

2026en

Ochiq kirishOltin

Litsenziya: cc-by

ABI

Annotatsiya

Silver quantum dots (Ag QDs) are emerging antibacterial nanomaterials whose activity depends not only on silver content or nanoscale size but also on structure–surface interactions. This review analyzes Ag QDs as structure–surface–function systems, highlighting the roles of quantum confinement, surface coordination, ligand/capping chemistry, colloidal stability, and synthesis-dependent variability. Evidence from green and biosynthesized Ag QDs, polymer-stabilized systems, silica/PAAc matrices, photoactive hybrids, Schiff-base-functionalized Ag₂S QDs, and targeted antimycobacterial platforms is critically discussed. Antibacterial performance is evaluated through biointerface interactions, oxidative stress, membrane disruption, intracellular damage, photo-assisted disinfection, ligand-controlled activity, and matrix-mediated localization. Key challenges, including inconsistent Ag QD definitions, limited mechanistic attribution, heterogeneous assays, toxicity concerns, reproducibility, scalability, and controlled silver accessibility, are examined. Overall, this review emphasizes that future Ag QD translation requires surface-engineered, mechanism-guided, and safety-oriented design strategies rather than empirical optimization of antibacterial potency alone.

Hali tarjima qilinmagan

Identifikatorlar

DOI: 10.1016/j.colcom.2026.100926

Iqtiboslar va manbalar

0 ta iqtibos79 ta foydalanilgan manba