Virusli gepatitlarning klinik kechishi va diagnostikasining zamonaviy xususiyatlari

Viral hepatitis remains a major concern in modern infectious disease medicine due to its widespread prevalence, the substantial proportion of asymptomatic cases, and the risk of developing chronic liver disease. This article examines contemporary features of the clinical course of hepatitis A, B, C, D, and E, analyzes differences between acute and chronic forms of infection, and discusses factors determining the risk of fibrosis, liver cirrhosis, and hepatocellular carcinoma. Particular attention is paid to modern diagnostic strategies, including serological testing, detection of viral nucleic acids, quantitative assessment of viral load, reflex testing, and non-invasive evaluation of liver status. An overview of recent international studies and clinical guidelines is presented. The findings indicate that improved diagnostic effectiveness is associated with a shift from a symptom-oriented approach to early infection detection and comprehensive laboratory and instrumental assessment of patients.

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