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Host chemodiversity-driven microbiome engineering for smart crops

Qianqian PanCollege of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, ChinaAdam OkorskiFaculty of Agriculture and Forestry, University of Warmia and Mazury in Olsztyn, Olsztyn 10-727, PolandJuan Ignacio VílchezUniversidade Nova de LisboaYusufjon GafforovCentral Asian Center for Development Studies, New Uzbekistan University, Tashkent 100007, UzbekistanMengcen WangState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang University, Hangzhou 310058, China
2026en
Ochiq kirishOlmos

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Breeding crops with multiple excellent traits represents a promising solution to food crises under changing climatic conditions. Chemodiversity mediates plant-microbiome interactions, and engineering this crosstalk offers a novel strategy to develop smart crops with enhanced resilience, yield and nutritional quality while mitigating trade-offs. Here, we propose a translational framework for engineering chemodiversity-microbiome crosstalk through molecular breeding of targeted metabolites, exogenous metabolite applications, and synthetic microbial communities, thereby accelerating chemodiversity-driven microbiome engineering toward trade-off-mitigated smart crops.

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