Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells
Hin ChuFrom the State Key Laboratory of Emerging Infectious DiseasesChe-Man ChanDepartments of Microbiology andXi ZhangDepartments of Microbiology andYixin WangDepartments of Microbiology andShuofeng YuanDepartments of Microbiology andJie ZhouDepartments of Microbiology andRex Au-YeungPathologyKong‐Hung SzeDepartments of Microbiology andDong YangDepartments of Microbiology andHuiping ShuaiDepartments of Microbiology andYuxin HouDepartments of Microbiology andCun LiDepartments of Microbiology andXiaoyu ZhaoDepartments of Microbiology andVincent Kwok‐Man PoonDepartments of Microbiology andSze LeungDepartments of Microbiology andMan Lung YeungCarol Yu Centre for InfectionJinghua YanCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101Guangwen Luthe West China Hospital Emergency Department, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan 610041, andDong‐Yan JinSchool of Biomedical Sciences, andGeorge F. GaoNAtioNAl Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (ChiNA CDC), Beijing 102206, ChiNAJasper Fuk‐Woo ChanFrom the State Key Laboratory of Emerging Infectious Diseases, [email protected]Kwok‐Yung YuenCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region
2018en
ABI
Annotatsiya
, the lineage C MERS-CoV and the lineage D bCoV-HKU9. The capacity of GRP78 to facilitate surface attachment of both a human coronavirus and a phylogenetically related bat coronavirus exemplifies the need for continuous surveillance of the evolution of animal coronaviruses to monitor their potential for human adaptations.
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