The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. ChristofkDepartment of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA;Matthew G. Vander HeidenDana Farber Cancer Institute, Boston, Massachusetts 02115, USA,Marian H. HarrisDepartment of Pathology, Children’s Hospital, Boston, Massachusetts 02115, USA,Arvind RamanathanChemical Biology Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA,Robert E. GersztenDonald W. Reynolds Cardiovascular Clinical Research Center on Atherosclerosis, Harvard Medical School, Boston, Massachusetts 02115, USA,Ru WeiChemical Biology Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA,Mark D. FlemingDepartment of Pathology, Children’s Hospital, Boston, Massachusetts 02115, USA,Stuart L. SchreiberChemical Biology Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA,Lewis C. CantleyDepartment of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA,
2008en
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