A composite nanocarrier to inhibit precipitation of the weakly basic drug in the gastrointestinal tract
Chunli ZhengDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing, ChinaYun LiDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing, ChinaZhenwei PengSchool of Basic Medical Sciences, Anhui Medical University, Hefei, ChinaXinyi HeDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing, ChinaJuan TaoLiang GeDepartment of Pharmaceutics, China Pharmaceutical University, Nanjing, ChinaYixin SunNanjing Children's Hospital, Nanjing Medical University, Nanjing, ChinaYunkai WuSchool of Basic Medical Sciences, Anhui Medical University, Hefei, China
2020en
ABI
Annotatsiya
.01) compared with the commercial formulation, indicating that the anticoagulant effect of DE was effectively improved. Therefore, the designed composite nanocarrier system of DE presents great potentials in improving the therapeutic efficiency and expanding the clinical applications of poorly water-soluble weakly basic drugs.
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