Preprint

Synthesis of Silver Modified Bioactive Glassy Materials with Antibacterial Properties via Facile and Low-Temperature Route

Isabel Gonzalo‐JuanTechnische Universitt Darmstadt, Institut fr Materialwissenschaft, Otto-Berndt-Strae 3, D-64287 Darmstadt, GermanyFangtong XieTechnische Universitt Darmstadt, Institut fr Materialwissenschaft, Otto-Berndt-Strae 3, D-64287 Darmstadt, GermanyMalin BeckerTechnische Universitt Darmstadt, Institut fr Materialwissenschaft, Otto-Berndt-Strae 3, D-64287 Darmstadt, GermanyDilshat U. TulyaganovTechnische Universitt Darmstadt, Institut fr Materialwissenschaft, Otto-Berndt-Strae 3, D-64287 Darmstadt, GermanyEmanuel IonescuTechnische Universitt Darmstadt, Institut fr Materialwissenschaft, Otto-Berndt-Strae 3, D-64287 Darmstadt, GermanyStefan LauterbachTechnische Universitt Darmstadt, Institut fr Angewandte Geowissenschaften, Schnittspahnstrasse 9, 64287 , Darmstadt, GermanyFrancesca RigottiAndreas FischerDivision of Vascular Signaling and Cancer (A270), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280 ,69120 Heidelberg, GermanyRalf RiedelTechnische Universitt Darmstadt, Institut fr Materialwissenschaft, Otto-Berndt-Strae 3, D-64287 Darmstadt, Germany

Preprints.orgrepository2020en

ABI

Annotatsiya

There is an increasing clinical need to develop novel biomaterials that combine regenerative and biocidal properties. In this work, we present the preparation of silver /silica based glassy bioactive (ABG) compositions via a facile, fast (20h), and low temperature (80 &deg;C) approach and their characterization. The fabrication process included the synthesis of the bioactive glass (BG) particles followed by the surface modification of the bioactive glass with silver nanoparticles. The microstructural features of ABG samples before and after exposure to simulated body fluid (SBF) as well as their ion release behavior during SBF test were evaluated using infrared spectrometry (FTIR), ultraviolet- visible (UV-Vis) spectroscopy, X-ray diffraction (XRD), electron microscopies (TEM and SEM) and optical emission spectroscopy (OES). The antibacterial properties of the experimental compositions were tested against Escherichia coli (E. coli). The results indicated that the prepared ABG materials possess antibacterial activity against E. coli, which is directly correlated with the glass surface modification.

Hali tarjima qilinmagan

Mavzular

Medical and Biological Ozone Research Bone Tissue Engineering Materials Laser-Ablation Synthesis of Nanoparticles

Identifikatorlar

DOI: 10.20944/preprints202010.0404.v1

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