Operative conversions of 3-carboxy-4-quinolones into 3-nitro-4-quinolones <i>via ipso</i>-nitration: potential antifilarial agents as inhibitors of <i>Brugia malayi</i> thymidylate kinase
Chandra S. AzadDivision of Medicinal and Process Chemistry CSIR-Central Drug Research InstituteVishal M. BalaramnavarGlobal Institute of Pharmaceutical Education and ResearchImran A. KhanIndiaPawan Kumar DohareyDivision of BiochemistryJitendra Kumar SaxenaDivision of BiochemistryAnil K. SaxenaIndia
2015en
ABI
Annotatsiya
An efficient, cost effective and green methodology for <italic>ipso</italic> nitration in the synthesis of the 3-nitro derivative of 3-carboxy 4-quinolones has been developed by the quantitative use of copper acetate and silver nitrate in water.
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