Prenylated Benzoic Acid Derivatives from <i>Ferula kuhistanica</i>
Bei ChenTokushima UniversityKazuyoshi KawazoeFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Josanjima, Tokushima 770-8501, Japan, and Academy of Sciences, Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanYoshihisa TakaishiTokushima UniversityGisho HondaTokushima UniversityMichiho ItoTokushima UniversityYoshio TakedaFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Josanjima, Tokushima 770-8501, Japan, and Academy of Sciences, Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanOlimjon K. KODZHIMATOVFaculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyoku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima, Josanjima, Tokushima 770-8501, Japan, and Academy of Sciences, Uzbekistan Institute of Botany, F. Khodzhaev, St. 32, 700143 Tashkent, UzbekistanOzodbek AshurmetovKyoto University
Ochiq kirish: yoʻq
ABI
Annotatsiya
Four new prenylated benzoic acid derivatives, kuhistanols A-D (1-4), along with one known compound, 3-farnesyl-p-hydroxybenzoic acid (5), have been isolated from the roots of the Uzbekistan medicinal plant, Ferula kuhistanica. Their structures were established on the basis of chemical and spectral evidence. Compound 4 showed a significant inhibitory effect on cytokine production in lipopolysaccharide-stimulated human peripheral mononuclear cells.
Hali tarjima qilinmagan