Maqola

Polysulfide Derivatives from <i>Ferula foetida</i>

Hong‐Quan DuanTokushima UniversityYoshihisa TakaishiTokushima UniversityMotoo ToriTokushima UniversityShigeru TakaokaTokushima UniversityGisho HondaTokushima UniversityMichiho ItoTokushima UniversityYoshio TakedaThe College of Pharmaceutical and Biotechnology, Tianjin University, 92 Weijin Road, Tianjin 300072, People's Republic of China, Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan, Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyou-ku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima,Olimjon K. KodzhimatovThe College of Pharmaceutical and Biotechnology, Tianjin University, 92 Weijin Road, Tianjin 300072, People's Republic of China, Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan, Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida Sakyou-ku, Kyoto 606-8501, Japan, Faculty of Integrated Arts and Sciences, University of Tokushima,K. KodzhimatovTokushima UniversityOzodbek AshurmetovTokushima University

2002en

ABI

Annotatsiya

The ethyl acetate-soluble fraction from a methanol extract of Ferula foetida has afforded six new sulfide derivatives, (E)-3-methylsulfinyl-2-propenyl sec-butyl disulfide (foetisulfide A) (1), (Z)-3-methylsulfinyloxy-2-propenyl sec-butyl disulfide (foetisulfide B) (2), (E)-3-methylsulfinyloxy-2-propenyl sec-butyl disulfide (foetisulfide C) (3), bis(3-methylthio-2E-propenyl) disulfide (foetisulfide D) (4), 3,4,5-trimethyl-2-thiophenecarboxylic acid (foetithiophene A) (5), 3,4,5-trimethyl-2-(methylsulfinyloxymethyl)thiophene (foetithiophene B) (6), along with six known compounds. The structures of 1-6 were established on the basis of spectroscopic studies, with the elucidation of 5 confirmed by single-crystal X-ray crystallography.

Hali tarjima qilinmagan

Identifikatorlar

DOI: 10.1021/np010541h

Iqtiboslar va manbalar

8 ta iqtibos0 ta foydalanilgan manba