Drugs as P-glycoprotein substrates, inhibitors, and inducers

Richard B. Kim572 RRBI Departments of Medicine and Pharmacology Division of Clinical Pharmacology, Vanderbilt University School of Medicine, 23rd Avenue at Pierce Avenue, Nashville, TN, 37232-6602, U.S.A

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Annotatsiya

In humans, there are two P-glycoprotein (P-gp) transporters encoded by MDR1 (PGY1) and MDR3 (also named MDR2 and PGY3) adjacently located at the chromosomal region 7q21 [1][2]. The encoded gene pro...

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DOI: 10.1081/dmr-120001389

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