PROGNOSTIC SIGNIFICANCE OF CYTOKINE PROFILE AND NEUROIMAGING MARKERS IN THE PROGRESSION OF PARKINSON'S DISEASE
E.I. AbduqodirovTashkent State Medical UniversityS.O InoyatovaTashkent State University of EconomicsM.U. KarimovaTashkent State Medical UniversityM.A. MaxamadxodjayevaTashkent State Medical UniversityQ.K. BoboyevTashkent State University of EconomicsN.A. OqiljonovaTashkent State University of EconomicsSh.Kh. BabakulovTashkent State University of EconomicsF.O. Tuxliyeva.Tashkent State University of Economics
Zenodo (CERN European Organization for Nuclear Research)repository2026
ABI
Annotatsiya
This scientific study analyzed 175 individuals, including 155 patients diagnosed with Parkinson's disease and 20 healthy controls, focusing on clinical subtypes (tremor-dominant, akinetic-rigid, and mixed forms). The research evaluated immunological (IL-1β, IL-6, TNF-α, IL-10), psychological (HADS, MMSE, VFT), and neurovisual (MRI) parameters. Results demonstrated significant differences in cytokine levels and cognitive-emotional status across subtypes. The findings underline the importance of a multidisciplinary approach to the diagnosis, classification, and personalized management of Parkinson’s disease.
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