ANALYSIS OF ADVERSE OUTCOMES IN THE EARLY POSTOPERATIVE PERIOD IN PATIENTS WITH INFECTED PANCREATIC NECROSIS

This scientific thesis analyzes adverse outcomes in the early postoperative period (EPP) among patients with infected pancreatic necrosis (IPN). Clinical studies were conducted on 124 patients with IPN. The control group included 62 patients (50%) with IPN and concomitant diabetes mellitus (DM), while the comparison group consisted of 62 patients (50%) with IPN without DM. The study demonstrated that patients with IPN associated with diabetes mellitus experienced organ dysfunction more frequently than patients without diabetes. In addition, the incidence of acute respiratory failure (ARF), acute renal failure (AcRF), and multiple organ failure (MOF) in the early postoperative period was significantly higher among patients with IPN and DM. These findings indicate that diabetes mellitus is an important risk factor contributing to the severity of postoperative complications and unfavorable outcomes in patients with infected pancreatic necrosis.

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